Chafik Ghayor Selected Research

N-methylpyrrolidone

10/2019	Epigenetic drugs as new therapy for tumor necrosis factor-α-compromised bone healing.
10/2018	The Bromodomain Inhibitor N-Methyl pyrrolidone Prevents Osteoporosis and BMP-Triggered Sclerostin Expression in Osteocytes.
1/2016	The bromodomain inhibitor N-methyl pyrrolidone reduced fat accumulation in an ovariectomized rat model.
9/2015	The epigenetically active small chemical N-methyl pyrrolidone (NMP) prevents estrogen depletion induced osteoporosis.
7/2015	N-methyl pyrrolidone (NMP) inhibits lipopolysaccharide-induced inflammation by suppressing NF-κB signaling.
7/2011	Inhibition of osteoclast differentiation and bone resorption by N-methylpyrrolidone.

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Chafik Ghayor Research Topics

Disease

5	Osteoporosis 12/2020 - 09/2015
3	Inflammation (Inflammations) 01/2020 - 07/2015
3	Bone Resorption 10/2018 - 07/2011
2	Wounds and Injuries (Trauma) 01/2018 - 09/2016
1	Osteonecrosis (Kienbock's Disease) 12/2020
1	Neoplasm Metastasis (Metastasis) 12/2020
1	Infertility (Sterility) 10/2020
1	Neoplasms (Cancer) 09/2016
1	Body Weight (Weight, Body) 01/2016
1	Weight Gain 01/2016
1	Male Infertility (Male Sterility) 04/2015

Drug/Important Bio-Agent (IBA)

6	N-methylpyrrolidoneIBA 10/2019 - 07/2011
3	dimethylacetamideIBA 10/2020 - 01/2017
3	Estrogens (Estrogen)FDA Link 10/2018 - 09/2015
2	Excipients (Suspending Agents)IBA 10/2020 - 01/2017
2	Pharmaceutical PreparationsIBA 10/2018 - 01/2017
2	CytokinesIBA 09/2015 - 07/2015
1	Denosumab FDA Link 12/2020
1	Antimicrobial PeptidesIBA 12/2020
1	Diphosphonates (Bisphosphonates)IBA 12/2020
1	DefensinsIBA 12/2020
1	AdipokinesIBA 01/2020
1	Therapeutic UsesIBA 10/2019
1	Bone Morphogenetic Protein 2IBA 10/2018
1	Bone SubstitutesIBA 01/2018
1	LigandsIBA 01/2017
1	LeptinIBA 01/2016
1	LipopolysaccharidesIBA 07/2015
1	ChemokinesIBA 07/2015
1	ProteomeIBA 07/2015
1	Cathepsin KIBA 07/2011

Therapy/Procedure

2	Therapeutics 12/2020 - 10/2019
2	Oral Surgery (Maxillofacial Surgery) 01/2018 - 09/2016
1	Ovariectomy (Oophorectomy) 01/2016
1	Spinal Fusion (Spondylosyndesis) 04/2015